Van de Ven Double Halts The Toffees' Run at New Home Ground
The Dutch defender became the initial backline player to net two goals in a Premier League game for Tottenham since Jan Vertonghen in March 2013.
Key points
The Spurs defender nods into the net twice in first half
The home side's defender has equalizer disallowed after video check
Senegalese midfielder nets final goal in dying moments
The defeat is Everton's initial at their new ground
The Tottenham defender found the net on two occasions as Spurs extended their unbeaten run in away games in the top division and delivered the Toffees their first defeat at Hill Dickinson Stadium.
The Toffees were unbeaten in their last five matches at their recently opened stadium at Bramley-Moore Dock, having left their historic home behind after more than a century at the conclusion of the previous campaign.
But Tottenham's leader the Dutchman struck twice from corners in the first half to put their impressive record at risk, and they were failed to mount a comeback before the midfielder - set up by ex-Everton forward the Brazilian - nodded in a third to seal the victory.
Jake O'Brien believed he had levelled the tally five minutes after Van de Ven's opener, glancing a bullet header past the Spurs keeper from an set-piece.
Beto, meanwhile, failed to convert a number of chances, while Vicario made a series of excellent saves to ensure Tottenham went five matches on the road without defeat in the English top flight.
But the VAR stepped in, advising the match official to review the goal on the screen and the official ruled that the winger and Iliman Ndiaye were in an illegal position and had impeded with the Tottenham goalkeeper.
The win moves Thomas Frank's side into third place in the Premier League, a handful of points off north London rivals and table-toppers the Gunners.
Everton remain in 14th position and sit half a dozen points ahead of the drop zone.
Tottenham analysis: The defender fulfils duties at each end of pitch
Following a uninspiring midweek display in the Champions League against the French side, where they managed a mere two shots on target, Frank chose Randal Kolo Muani in attack instead of former Toffees player Richarlison.
The new arrival was failed to make much of an impact before being replaced for Richarlison after 60 minutes on the field, but it turns out he wasn't needed in the end.
Defender the Dutchman converted into an offensive threat to be reckoned with.
Tottenham's opening strike came from a cleverly executed set-piece play, with the midfielder directing the ball back across the face of goal for an free Van de Ven to head home.
And the captain - filling in as skipper in Cristian Romero's unavailability - added his second in added time as he rose above the England keeper to nod in.
The Dutchman was equally outstanding in defensive duties, partnering effectively with his defensive colleague as the duo handled excellently with the numerous deliveries thrown their way by the opposition.
Everton analysis: Toffees missing striker's instinct
Everton's new home had been a happy hunting ground, but it appears the freshness may have worn off slightly and fans flocked to the exits after the midfielder's final goal for Tottenham.
The end in Everton's unbeaten home run won't be a major concern for David Moyes, but their attacking woes are.
Beto and the other striker - the Toffees' pair of established strikers - had scored only a single goal between them before the weekend's match.
And they were failed to contribute to that poor record on a damp and dreary evening on Merseyside.
Beto's performance was epitomized when he chose to bicycle-kick a clear chance from near the goal, even with having room and opportunity to readjust for a simpler attempt that would have challenged Vicario.
Barry, as well, was unable to make an impact after replacing Beto in the second half.
It was not for a shortage of opportunity. Most of Everton's attacks came through Grealish and Ndiaye, who tirelessly whipped threatening crosses into the Spurs box.
Upcoming fixtures for these two sides?
The Toffees: The team travel to Sunderland in the top flight on early November at 8 PM.
Spurs: The London club travel to Newcastle's ground on Wednesday, 29 October for their next round League Cup tie against the Magpies.